K9 Advantix II for Large Dogs provides broad-spectrum, waterproof protection against fleas, ticks, mosquitoes, biting flies, and lice through contact-kill action without painful biting. This once-monthly topical treatment combines imidacloprid, permethrin, and pyriproxyfen to kill all flea life stages, prevent re-infestation, and provide four weeks of continuous protection.
Imidacloprid 8.80%, Permethrin 44.00%, Pyriproxyfen 0.44%
Propylene glycol, benzyl alcohol, polyethylene glycol, and other inert ingredients
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Variants |
Active Ingredients |
||||
|
Weight Range |
Box Color |
Tube Volume |
Imidacloprid Content |
Permethrin Content |
Pyriproxyfen Content |
|
4-10 lbs |
Green |
0.4 mL |
3.52 mg |
17.6 mg |
0.176 mg |
|
11-20 lbs |
Teal |
1.0 mL |
8.8 mg |
44 mg |
0.44 mg |
|
21-55 lbs |
Red |
2.5 mL |
22 mg |
110 mg |
1.1 mg |
|
Over 55 lbs |
Blue |
4.0 mL |
35.2 mg |
176 mg |
1.76 mg |
We offer ground, express, priority, and international delivery; see our shipping policy for details.
For return instructions or product concerns, please refer to our detailed refund policy.
Ans: K9 Advantix II Topical Flea & Tick Protection for Large Dogs targets fleas and ticks and also helps protect against mosquitoes, biting flies, and lice. The topical application kills and repels through contact for month-long coverage.
Ans: K9 Advantix II Topical Flea & Tick Protection for Large Dogs is formulated for dogs weighing 21–55 lbs. Using the correct weight range helps ensure proper dosing and consistent protection for the full month.
Ans: Apply one tube of K9 Advantix II to a dog weighing 21–55 lbs every 30 days. Monthly application helps maintain continuous protection and reduces the chance of new flea or tick infestations.
Ans: Part the hair and apply the full tube directly on the skin in 4–6 spots along the back from the shoulders to tail base. Avoid placing too much in one spot to prevent runoff.
Ans: K9 Advantix II can be used around bathing routines, but the dog must be dry at application. Keep the dog dry for 24 hours after use to help the waterproof protection set properly.
Ans: K9 Advantix II Large Dogs is only for dogs and puppies 7 weeks and older that weigh at least 21 lbs. Always confirm age and weight before applying any topical parasite control product.
Ans: K9 Advantix II should never be used on cats because the formulation can be dangerous or fatal. Keep cats away from treated dogs until the application area is completely dry, and contact a veterinarian immediately if exposure occurs.
Ans: Some dogs may show temporary skin irritation, such as redness or scratching. Vomiting, diarrhea, lethargy, or agitation have also been reported. Contact a veterinarian if any reaction persists, worsens, or appears severe.
These antibiotics have saved us $1000’s of dollars in vet bills.
Great product just as described! Received promptly after ordering.
Fast shipping and packed safely. Haven’t had to take them yet but on hand when I do.
Great product, slow shipping.
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