Frontline Plus for Extra Large Dogs (89-132 lbs) Red Box

Monthly Topical Flea & Tick Spot Treatment

Product Description

Frontline Plus for Extra Large Dogs provides fast-acting, long-lasting protection against fleas, ticks, and chewing lice through waterproof topical application. This dual-action formula combines fipronil and (S)-methoprene to kill adult fleas, eggs, larvae, and all tick life stages while preventing re-infestation for 30 days. Frontline Plus ensures your dog stays comfortable and parasite-free, offering peace of mind with reliable, month-long protection. 

Benefits

• Dual Action: Kills adult fleas and prevents all flea life stages from developing.
• Tick Protection: Eliminates deer, brown dog, American dog, and Lone Star ticks effectively.
• Disease Prevention: Kills ticks that may transmit Lyme disease and Rocky Mountain spotted fever.
• Waterproof Formula: Maintains effectiveness after bathing, swimming, or rain exposure for 24 hours.
• Long-Lasting: A single application provides continuous protection for 30 days against reinfestation.

Ingredients

Active Ingredients

Fipronil and (S)-methoprene.

Composition Table 

Ingredient	Percentage
Fipronil	9.8%
(S)-Methoprene	8.8%
Other Ingredients	81.4%
Total	100%

Variants

Variants			Active Ingredients
Weight Range	Box Color	Tube Volume	Fipronil Content	(S)-methoprene Content
5-22 lbs	Orange	0.67 mL	67 mg	60.3 mg
23-44 lbs	Blue	1.34 mL	134 mg	120.6 mg
45-88 lbs	Purple	2.68 mL	268 mg	241.2 mg
89-132 lbs	Red	4.02 mL	402 mg	361.8 mg

How to Use

Directions for Use 

• Read Instructions Carefully: Always read the entire label before use to ensure proper and lawful product application.
• Human and Animal Safety: Do not allow children to apply this product; it is for use on dogs only.
• Preparation Before Application: Use scissors to separate one blister, cut along the dotted line, and peel the foil.
• Correct Application Method: Hold the applicator upright, part your dog’s hair, and apply contents directly to visible skin.
• Usage Restrictions: Avoid using on dogs younger than eight weeks or weighing less than forty-five pounds.
• Product Effectiveness: Frontline Plus remains effective even after water immersion, bathing, or sunlight exposure for lasting protection.

Additional Information

Frequency of Application 

• Monthly Application Required: Apply Frontline Plus monthly to break the flea life cycle and control infestations effectively for 30 days.
• Long-Lasting Protection: Frontline Plus controls fleas, flea eggs, and larvae for up to three months after application.
• Tick Control: Kills ticks for at least one month, including all life stages such as larvae, nymphs, and adults.
• Disease Prevention: Helps prevent diseases transmitted by ticks, including anaplasmosis, Rocky Mountain spotted fever, and Lyme disease.
• Lice and Mite Control: Effectively kills chewing lice and aids in controlling sarcoptic mange infestations with regular monthly treatments.
• Reapplication Guidance: Do not reapply Frontline Plus within 30 days to avoid overexposure or reduced effectiveness.

Possible Side Effects

• Monitor After Application: Dogs may experience mild irritation or temporary skin reactions after the product is applied.
• Observe for Worsening Symptoms: If irritation or sensitivity worsens in the next few days, contact your veterinarian immediately for advice. 
• Veterinary Consultation Required: Consult a veterinarian promptly if redness, itching, or discomfort persists or becomes more severe.
• Normal Mild Reaction: Minor temporary irritation at the site of application is usually not a cause for concern.
• Discontinue if Severe Reaction: Stop using the product if your dog shows strong adverse effects and contact your veterinarian immediately.

Shipping & Return

We offer ground, express, priority, and international delivery; see our shipping policy for details.

For return instructions or product concerns, please refer to our detailed refund policy.

Frequently Asked Questions

Q1: How often should I apply Frontline Plus to my dog?

Ans: Frontline Plus needs to be applied once a month to stop the flea life cycle and control flea and tick infestations. Applying it every month ensures ongoing protection and prevents re-infestation throughout the entire month. 

Q2: Is Frontline Plus safe for puppies?

Ans: Yes, Frontline Plus is safe for puppies aged 8 weeks or older, weighing a minimum of 5 pounds. Make sure to select the correct weight-based formulation for your puppy, and consult your veterinarian if unsure.

Q3: Can my dog swim or bathe after using Frontline Plus?

Ans: Yes, once Frontline Plus dries (about 24 hours), your dog can swim, bathe, or be exposed to rain without reducing the effectiveness of the product. This waterproof formula ensures long-term protection even in wet conditions.

Q4: What should I do if my dog experiences an adverse reaction?

Ans: If your dog shows signs of skin irritation or unease at the site of application site, it is usually temporary. However, if the symptoms worsen, consult your veterinarian immediately for guidance and care.

Q5: Can Frontline Plus help prevent diseases transmitted by ticks?

Ans: Yes, Frontline Plus eliminates ticks that could carry Lyme disease, Rocky Mountain spotted fever, and other tick-borne illnesses. Regular use of this product helps protect your dog from these harmful illnesses and keeps them safe from ticks.